Anti-SF3A3 Polyclonal Antibody (HB387014)

Name: Anti-SF3A3 Polyclonal Antibody
Brand: abinScience
SKU: HB387014
Price: 168 USD
Availability: InStock

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100ug

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Каталожный номер

HB387014

Описание

Anti-SF3A3 Polyclonal Antibody (HB387014) is a rabbit polyclonal antibody detecting Splicing factor 3A subunit 3; SF3a60; Spliceosome-associated protein 61; SAP 61; SF3A3; SAP61 in ELISA, IHC, WB. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human, Mouse

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant human SF3A3 (Met1-Leu501).

Цель

Splicing factor 3A subunit 3; SF3a60; Spliceosome-associated protein 61; SAP 61; SF3A3; SAP61

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

Q12874, Q9D554

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Splicing factor 3A subunit 3 (SF3A3) is a ~58 kDa protein. Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs. The 17S U2 SnRNP complex (1) directly participates in early spliceosome assembly and (2) mediates recognition of the intron branch site during pre-mRNA splicing by promoting the selection of the pre-mRNA branch-site adenosine, the nucleophile for the first step of splicing. Within the 17S U2 SnRNP complex, SF3A3 is part of the SF3A subcomplex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes.

1. Das, R. et al. (2000) Molecular cell 5, 779-87. PMID: 10882114

2. Nesic, D. et al. (2001) Molecular and cellular biology 21, 6406-17. PMID: 11533230

3. Zhang, Z. et al. (2020) Nature 583, 310-313. PMID: 32494006

4. Tholen, J. et al. (2022) Science (New York, N.Y.) 375, 50-57. PMID: 34822310

5. Chiara, MD. et al. (1994) Proceedings of the National Academy of Sciences of the United States of America 91, 6403-7. PMID: 8022796

6. Zhang, X. et al. (2018) Cell research 28, 307-322. PMID: 29360106

7. Zhan, X. et al. (2018) Cell research 28, 1129-1140. PMID: 30315277

Примечание

For research use only

Изображения

Ссылки

Даташит

Anti-SF3A3 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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Anti-SF3A3 Polyclonal Antibody (HB387014)

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