

| Número de catálogo | HV050014 | ||||||||
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| Descripción |
Anti-SIGIRR Polyclonal Antibody (HV050014) is a rabbit polyclonal antibody detecting SIGIRR in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human SIGIRR (Met1-His118). | ||||||||
| Objetivo | TIR8, Toll/interleukin-1 receptor 8, Single Ig IL-1R-related molecule, Single Ig IL-1-related receptor, Single immunoglobulin domain-containing IL1R-related protein, SIGIRR | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q6IA17 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Single Ig IL-1-related receptor (SIGIRR) is a ~45 kDa protein. Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP. | ||||||||
| Nota | For research use only. |
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