

| Número de catálogo | VK617034 | ||||
|---|---|---|---|---|---|
| Descripción |
Anti-SIV gp120 Polyclonal Antibody (VK617034) is a rabbit polyclonal antibody detecting gp120 in ELISA, IHC, WB.
Highlights
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| Reactividad de especies | Simian immunodeficiency virus (SIV) | ||||
| Aplicaciones | ELISA, IHC, WB | ||||
| Especie huésped | Rabbit | ||||
| Clonalidad | Polyclonal | ||||
| Isotipo | IgG | ||||
| Inmunógeno | E. coli - derived recombinant SIV gp120 (Ile20-Ser523). | ||||
| Objetivo | Envelope glycoprotein gp160, Env polyprotein, Surface protein gp120, SU, Glycoprotein 120, gp120, Transmembrane protein gp41, TM, Glycoprotein 32, gp32, env | ||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||
| Purificación | Purified by antigen affinity column. | ||||
| Número de acceso | P11267, P08810, P05884, P05885 | ||||
| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Fondo | Envelope glycoprotein gp160 (gp120) is a ~101 kDa protein. The surface protein gp120 (SU) attaches the virus to the host lymphoid cell by binding to the primary receptor CD4. This interaction induces a structural rearrangement creating a high affinity binding site for a chemokine coreceptor like CCR5. This peculiar 2 stage receptor-interaction strategy allows gp120 to maintain the highly conserved coreceptor-binding site in a cryptic conformation, protected from neutralizing antibodies. These changes are transmitted to the transmembrane protein gp41 and are thought to activate its fusogenic potential by unmasking its fusion peptide. | ||||
| Nota | For research use only |
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