

| Número de catálogo | VK100034 | ||||
|---|---|---|---|---|---|
| Descripción |
Anti-SIV VIF Polyclonal Antibody (VK100034) is a rabbit polyclonal antibody detecting vif protein in ELISA, IHC, WB.
Highlights
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| Reactividad de especies | Simian immunodeficiency virus (SIV) | ||||
| Aplicaciones | ELISA, IHC, WB | ||||
| Especie huésped | Rabbit | ||||
| Clonalidad | Polyclonal | ||||
| Isotipo | IgG | ||||
| Inmunógeno | E. coli - derived recombinant SIV VIF (Met1-Ser176). | ||||
| Objetivo | vif protein, vif | ||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||
| Purificación | Purified by antigen affinity column. | ||||
| Número de acceso | Q02841 | ||||
| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Fondo | Virion infectivity factor (VIF) is a ~26 kDa protein. Counteracts the innate antiviral activity of APOBEC3G. Forms a complex with host APOBEC3G thus preventing the entry of this lethally hypermutating enzyme into progeny virions. Functions as an adapter molecule, recruiting APOBEC3G to the ubiquitin-proteasome machinery. Targets APOBEC3G for degradation through the assembly with elongin BC complex, CUL5 and RBX1. Binds viral RNA and affects the stability of viral nucleoprotein core. | ||||
| Nota | For research use only. |
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