Anti-SKP1 Polyclonal Antibody (HX846014)

Name: Anti-SKP1 Polyclonal Antibody
Brand: abinScience
SKU: HX846014
Price: 168 USD
Availability: InStock

Fiche technique Partager le produit Copier les informations

Prix(USD) :

Spécification :

50ug
100ug

Nombre :

Contactez-nous

Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HX846014

Description

Anti-SKP1 Polyclonal Antibody (HX846014) is a rabbit polyclonal antibody detecting SKP1 in ELISA, IHC, WB. Suitable for Bovine, Cavia porcellus, Chicken, Human, and Macaca fascicularis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human SKP1 (Met1-Lys163).

Cible

p19A, Organ of Corti protein 2, EMC19, SKP1, Organ of Corti protein II, OCP2, OCP-2, RNA polymerase II elongation factor-like protein, Cyclin-A/CDK2-associated protein p19, OCP-II, p19skp1, TCEB1L, S-phase kinase-associated protein 1, SIII, Transcription elongation factor B polypeptide 1-like, SKP1A

Purification

Purified by antigen affinity column.

Numéro d'accès

P63208

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

S-phase kinase-associated protein 1 (SKP1) is a ~18 kDa protein. Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA.

1. Man, X. et al. (2015) European journal of cell biology 94, 162-72. PMID: 25704143

2. Hopf, LVM. et al. (2022) Nature structural & molecular biology 29, 854-862. PMID: 35982156

3. Cao, Y. et al. (2023) The EMBO journal 42, e113033. PMID: 36896912

Note

For research use only.

Images

Reférences

Fiche technique

Anti-SKP1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai