Anti-SLC12A3 Polyclonal Antibody (HX864014)

Name: Anti-SLC12A3 Polyclonal Antibody
Brand: abinScience
SKU: HX864014
Price: 168 USD
Availability: InStock

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Spécification :

50ug
100ug

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Aperçu
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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HX864014

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human SLC12A3 (Glu3-Cys146).

Cible

TSC, SLC12A3, NCC, Solute carrier family 12 member 3, Na-Cl cotransporter, Thiazide-sensitive sodium-chloride cotransporter, Na-Cl symporter

Purification

Purified by antigen affinity column.

Numéro d'accès

P55017

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Solute carrier family 12 member 3 (SLC12A3) is a ~113 kDa protein. Electroneutral sodium and chloride ion cotransporter, which acts as a key mediator of sodium and chloride reabsorption in kidney distal convoluted tubules. Also acts as a receptor for the pro-inflammatory cytokine IL18, thereby contributing to IL18-induced cytokine production, including IFNG, IL6, IL18 and CCL2. May act either independently of IL18R1, or in a complex with IL18R1.

1. Richardson, C. et al. (2008) Journal of cell science 121, 675-84. PMID: 18270262

2. Cruz-Rangel, S. et al. (2011) American journal of physiology. Cell physiology 301, C601-8. PMID: 21613606

3. Glaudemans, B. et al. (2012) European journal of human genetics : EJHG 20, 263-70. PMID: 22009145

4. Nan, J. et al. (2022) Science advances 8, eadd7176. PMID: 36351028

5. Fan, M. et al. (2023) Nature 614, 788-793. PMID: 36792826

Note

For research use only.

Images

Reférences

Fiche technique

Anti-SLC12A3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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