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Anti-SLC1A1 Polyclonal Antibody (HW669014)

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Aperçu
Numéro de catalogueHW669014
Description
Anti-SLC1A1 Polyclonal Antibody (HW669014) is a rabbit polyclonal antibody detecting SLC1A1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human SLC1A1 (Ser115-Gly209).
Cible EAAC1, EAAT3, Sodium-dependent glutamate/aspartate transporter 3, Solute carrier family 1 member 1, Excitatory amino-acid carrier 1, SLC1A1, Excitatory amino acid transporter 3, Neuronal and epithelial glutamate transporter
Purification Purified by antigen affinity column.
Numéro d'accès P43005
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Excitatory amino acid transporter 3 (SLC1A1) is a ~57 kDa protein. Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Can also transport L-cysteine. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli.

1. Bailey, CG. et al. (2011) The Journal of clinical investigation 121, 446-53. PMID: 21123949
2. Abousaab, A. et al. (2016) The Journal of membrane biology 249, 239-49. PMID: 26690923
3. Qiu, B. et al. (2021) Science advances 7. PMID: 33658209
4. Arriza, JL. et al. (1994) The Journal of neuroscience : the official journal of the Society for Neuroscience 14, 5559-69. PMID: 7521911
5. Kanai, Y. et al. (1994) The Journal of biological chemistry 269, 20599-606. PMID: 7914198
6. Zerangue, N. et al. (1996) Nature 383, 634-7. PMID: 8857541
Note For research use only.
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Reférences
Fiche technique
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-SLC1A1 Polyclonal Antibody

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