Anti-SLC1A4 Polyclonal Antibody (HA640014)

Name: Anti-SLC1A4 Polyclonal Antibody
Brand: abinScience
SKU: HA640014
Price: 168 USD
Availability: InStock

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Spécification :

50ug
100ug

Nombre :

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SDS

Aperçu

Numéro de catalogue

HA640014

Description

Anti-SLC1A4 Polyclonal Antibody (HA640014) is a rabbit polyclonal antibody detecting Neutral amino acid transporter A; Alanine/serine/cysteine/threonine transporter 1; ASCT-1; Solute carrier family 1 member 4; SLC1A4; ASCT1; SATT in ELISA, IHC, WB. Suitable for Human and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant human SLC1A4 (Lys140-Thr216).

Cible

Neutral amino acid transporter A; Alanine/serine/cysteine/threonine transporter 1; ASCT-1; Solute carrier family 1 member 4; SLC1A4; ASCT1; SATT

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

P43007, A2VDL4

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Neutral amino acid transporter A (SLC1A4) is a ~55 kDa protein. Sodium-coupled antiporter of neutral amino acids. In a tri-substrate transport cycle, exchanges neutral amino acids between the extracellular and intracellular compartments, coupled to the inward cotransport of at least one sodium ion. Exchanges neutral amino acids such as L- and D-serine, L-threonine, L-asparagine and L-alanine in a bidirectional way. Involved in homeostasis of D-serine, a coagonist of synaptic NMDA receptors. In astrocytes at excitatory synapses, mediates electrogenic D-serine influx coupled to L-serine efflux and L-serine shuttling to neurons for de novo D-serine synthesis.

1. Scopelliti, AJ. et al. (2014) The Journal of biological chemistry 289, 17468-79. PMID: 24808181

2. Foster, AC. et al. (2016) PloS one 11, e0156551. PMID: 27272177

3. Stehantsev, P. et al. (2021) Computational and structural biotechnology journal 19, 5246-5254. PMID: 34630942

4. Zerangue, N. et al. (1996) The Journal of biological chemistry 271, 27991-4. PMID: 8910405

5. Pinilla-Tenas, J. et al. (2003) The Journal of membrane biology 195, 27-32. PMID: 14502423

6. Damseh, N. et al. (2015) Journal of medical genetics 52, 541-7. PMID: 26041762

7. Arriza, JL. et al. (1993) The Journal of biological chemistry 268, 15329-32. PMID: 8101838

8. Shafqat, S. et al. (1993) The Journal of biological chemistry 268, 15351-5. PMID: 8340364

Note

For research use only

Images

Reférences

Fiche technique

Anti-SLC1A4 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-SLC1A4 Polyclonal Antibody (HA640014)

Aperçu

Images

Reférences

Fiche technique

SDS