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| カタログ番号 | HA697014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-SLC1A6 Polyclonal Antibody (HA697014) is a rabbit polyclonal antibody detecting Excitatory amino acid transporter 4; Sodium-dependent glutamate/aspartate transporter; Solute carrier family 1 member 6; SLC1A6; EAAT4 in ELISA, IHC, WB. Suitable for Human, Dog, Mouse, and Rat.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human SLC1A6 (Ile153-Ser262). | ||||||||
| ターゲット | Excitatory amino acid transporter 4; Sodium-dependent glutamate/aspartate transporter; Solute carrier family 1 member 6; SLC1A6; EAAT4 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P48664, Q9N1R2, O35544, O35921 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Excitatory amino acid transporter 4 (SLC1A6) is a ~61 kDa protein. Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (Probable). 1. Abousaab, A. et al. (2016) The Journal of membrane biology 249, 239-49. PMID: 26690923 2. Fairman, WA. et al. (1995) Nature 375, 599-603. PMID: 7791878 | ||||||||
| 注意事項 | For research use only |
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