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| カタログ番号 | HB435014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-SLC4A10 Polyclonal Antibody (HB435014) is a rabbit polyclonal antibody detecting Sodium-driven chloride bicarbonate exchanger; Solute carrier family 4 member 10; SLC4A10; NBCN2; NCBE in ELISA, IHC, WB. Suitable for Human, Bovine, Rat, and Mouse.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human SLC4A10 (Asp93-Trp432). | ||||||||
| ターゲット | Sodium-driven chloride bicarbonate exchanger; Solute carrier family 4 member 10; SLC4A10; NBCN2; NCBE | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q6U841, Q32LP4, Q80ZA5, Q5DTL9 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Sodium-driven chloride bicarbonate exchanger (SLC4A10) is a ~125 kDa protein. Sodium/bicarbonate cotransporter which plays an important role in regulating intracellular pH. Has been shown to act as a sodium/bicarbonate cotransporter in exchange for intracellular chloride. Has also been shown to act as a sodium/biocarbonate cotransporter which does not couple net influx of bicarbonate to net efflux of chloride, with the observed chloride efflux being due to chloride self-exchange. Controls neuronal pH and may contribute to the secretion of cerebrospinal fluid. Acting on presynaptic intracellular pH, it promotes GABA release, reduces the excitability of CA1 pyramidal neurons, and modulates short-term synaptic plasticity. 1. Parker, MD. et al. (2008) The Journal of biological chemistry 283, 12777-88. PMID: 18319254 | ||||||||
| 注意事項 | For research use only |
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