

| Каталожный номер | HB435014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-SLC4A10 Polyclonal Antibody (HB435014) is a rabbit polyclonal antibody detecting Sodium-driven chloride bicarbonate exchanger; Solute carrier family 4 member 10; SLC4A10; NBCN2; NCBE in ELISA, IHC, WB. Suitable for Human, Bovine, Rat, and Mouse.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant human SLC4A10 (Asp93-Trp432). | ||||||||
| Цель | Sodium-driven chloride bicarbonate exchanger; Solute carrier family 4 member 10; SLC4A10; NBCN2; NCBE | ||||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q6U841, Q32LP4, Q80ZA5, Q5DTL9 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Sodium-driven chloride bicarbonate exchanger (SLC4A10) is a ~125 kDa protein. Sodium/bicarbonate cotransporter which plays an important role in regulating intracellular pH. Has been shown to act as a sodium/bicarbonate cotransporter in exchange for intracellular chloride. Has also been shown to act as a sodium/biocarbonate cotransporter which does not couple net influx of bicarbonate to net efflux of chloride, with the observed chloride efflux being due to chloride self-exchange. Controls neuronal pH and may contribute to the secretion of cerebrospinal fluid. Acting on presynaptic intracellular pH, it promotes GABA release, reduces the excitability of CA1 pyramidal neurons, and modulates short-term synaptic plasticity. 1. Parker, MD. et al. (2008) The Journal of biological chemistry 283, 12777-88. PMID: 18319254 | ||||||||
| Примечание | For research use only |
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