

| Каталожный номер | HC020014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-SLC7A10 Polyclonal Antibody (HC020014) is a rabbit polyclonal antibody detecting Asc-type amino acid transporter 1; Asc-1; Solute carrier family 7 member 10; SLC7A10; ASC1 in ELISA, IHC, WB. Suitable for Human, Rabbit, Rat, and Mouse.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant human SLC7A10 (Ala2-Glu39&Met291-Gly312&Arg470-Gln523). | ||||||||
| Цель | Asc-type amino acid transporter 1; Asc-1; Solute carrier family 7 member 10; SLC7A10; ASC1 | ||||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q9NS82, Q9N1Q4, Q9WVR6, Q9QXW9, Q9UHI5 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Asc-type amino acid transporter 1 (SLC7A10) is a ~56 kDa protein. Associates with SLC3A2/4F2hc to form a functional heterodimeric complex that translocates small neutral L- and D-amino acids across the plasma membrane. Preferentially mediates exchange transport, but can also operate via facilitated diffusion. Acts as a major transporter for glycine, L- and D-serine in the central nervous system. At the spinal cord and brainstem regulates glycine metabolism and glycinergic inhibitory neurotransmission by providing for glycine de novo synthesis from L-serine and glycine recycling from astrocytes to glycinergic motor neurons. At Schaffer collateral-CA1 synapses mediates D-serine and glycine release that modulates post-synaptic activation of NMDA receptors and excitatory glutamatergic transmission. 1. Nakauchi, J. et al. (2000) Neuroscience letters 287, 231-5. PMID: 10863037 | ||||||||
| Примечание | For research use only |
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