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Anti-SND1 Polyclonal Antibody (HV078014)

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Vista general
Número de catálogoHV078014
Descripción
Anti-SND1 Polyclonal Antibody (HV078014) is a rabbit polyclonal antibody detecting SND1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pongo abelii.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human SND1 (Ala650-Arg910).
Objetivo TDRD11, SND1, p100 co-activator, Staphylococcal nuclease domain-containing protein 1, Tudor domain-containing protein 11, EBNA2 coactivator p100, 100 kDa coactivator
Purificación Purified by antigen affinity column.
Número de acceso Q7KZF4
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Staphylococcal nuclease domain-containing protein 1 (SND1) is a ~101 kDa protein. Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition. Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for STAT5.

1. Li, CL. et al. (2008) Nucleic acids research 36, 3579-89. PMID: 18453631
2. Elbarbary, RA. et al. (2017) Science (New York, N.Y.) 356, 859-862. PMID: 28546213
3. Yang, J. et al. (2002) The EMBO journal 21, 4950-8. PMID: 12234934
4. Leverson, JD. et al. (1998) Molecular cell 2, 417-25. PMID: 9809063
Nota For research use only.
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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