Anti-SND1 Polyclonal Antibody (HV078014)

Name: Anti-SND1 Polyclonal Antibody
Brand: abinScience
SKU: HV078014
Price: 168 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HV078014

Description

Anti-SND1 Polyclonal Antibody (HV078014) is a rabbit polyclonal antibody detecting SND1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human SND1 (Ala650-Arg910).

Cible

TDRD11, SND1, p100 co-activator, Staphylococcal nuclease domain-containing protein 1, Tudor domain-containing protein 11, EBNA2 coactivator p100, 100 kDa coactivator

Purification

Purified by antigen affinity column.

Numéro d'accès

Q7KZF4

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Staphylococcal nuclease domain-containing protein 1 (SND1) is a ~101 kDa protein. Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition. Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for STAT5.

1. Li, CL. et al. (2008) Nucleic acids research 36, 3579-89. PMID: 18453631

2. Elbarbary, RA. et al. (2017) Science (New York, N.Y.) 356, 859-862. PMID: 28546213

3. Yang, J. et al. (2002) The EMBO journal 21, 4950-8. PMID: 12234934

4. Leverson, JD. et al. (1998) Molecular cell 2, 417-25. PMID: 9809063

Note

For research use only.

Images

Reférences

Fiche technique

Anti-SND1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

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