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| カタログ番号 | HV078014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-SND1 Polyclonal Antibody (HV078014) is a rabbit polyclonal antibody detecting SND1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pongo abelii.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SND1 (Ala650-Arg910). | ||||||||
| ターゲット | TDRD11, SND1, p100 co-activator, Staphylococcal nuclease domain-containing protein 1, Tudor domain-containing protein 11, EBNA2 coactivator p100, 100 kDa coactivator | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q7KZF4 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Staphylococcal nuclease domain-containing protein 1 (SND1) is a ~101 kDa protein. Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition. Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for STAT5. 1. Li, CL. et al. (2008) Nucleic acids research 36, 3579-89. PMID: 18453631 2. Elbarbary, RA. et al. (2017) Science (New York, N.Y.) 356, 859-862. PMID: 28546213 3. Yang, J. et al. (2002) The EMBO journal 21, 4950-8. PMID: 12234934 4. Leverson, JD. et al. (1998) Molecular cell 2, 417-25. PMID: 9809063 | ||||||||
| 注意事項 | For research use only. |
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