

| Каталожный номер | HX841014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-SORD Polyclonal Antibody (HX841014) is a rabbit polyclonal antibody detecting SORD in ELISA, IHC, WB. Suitable for Human, Bovine, Macaca fascicularis, Ovis aries, and Pongo abelii.
Highlights
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human SORD (Ala98-Gln355). | ||||||||
| Цель | (R, R)-butanediol dehydrogenase, RDH, Polyol dehydrogenase, Sorbitol dehydrogenase, Ribitol dehydrogenase, SORD, Xylitol dehydrogenase, XDH, L-iditol 2-dehydrogenase, SDH | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q00796 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Sorbitol dehydrogenase (SORD) is a ~38 kDa protein. Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols. Is mostly active with D-sorbitol (D-glucitol), L-threitol, xylitol and ribitol as substrates, leading to the C2-oxidized products D-fructose, L-erythrulose, D-xylulose, and D-ribulose, respectively. Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism. The polyol pathway is believed to be involved in the etiology of diabetic complications, such as diabetic neuropathy and retinopathy, induced by hyperglycemia. May play a role in sperm motility by using sorbitol as an alternative energy source for sperm motility. 1. Maret, W. et al. (1988) Biochemistry 27, 1622-8. PMID: 3365415 2. Pauly, TA. et al. (2003) Structure (London, England : 1993) 11, 1071-85. PMID: 12962626 3. Safi, SZ. et al. (2014) BioMed research international 2014, 801269. PMID: 25105142 4. Dewanjee, S. et al. (2018) European journal of pharmacology 833, 472-523. PMID: 29966615 5. Frenette, G. et al. (2006) Journal of andrology 27, 233-9. PMID: 16278369 | ||||||||
| Примечание | For research use only. |
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