中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | ZA049013 | ||||||
|---|---|---|---|---|---|---|---|
| 種反応性 | Crotalus durissus terrificus, Crotalus scutulatus scutulatus | ||||||
| アプリケーション | ELISA, FCM, IF, SPR, WB | ||||||
| 宿主種 | Mouse | ||||||
| クローン性 | Monoclonal | ||||||
| アイソタイプ | IgG2a | ||||||
| クローンID | Al0G | ||||||
| ターゲット | Phospholipase A2 crotoxin basic subunit CBc, CB1, CTX subunit CBc, svPLA2, 3.1.1.4, Phosphatidylcholine 2-acylhydrolase, Basic phospholipase A2 Mtx-b, svPLA2, 3.1.1.4, Mojave toxin basic chain, Phosphatidylcholine 2-acylhydrolase, Phospholipase A2 CB1, Crotalus durissus terrificus (South American rattlesnake), Crotalus scutulatus scutulatus (Mojave rattlesnake) | ||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||
| 純度 | >95% as determined by SDS-PAGE. | ||||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||||
| アクセッション番号 | P62022, P62023 | ||||||
| RRID | Anti-South American/Mojave rattlesnake crotoxin Antibody (Al0G) (abinScience Cat# ZA049013, RRID:AB_3729020) |
||||||
| 形態 | Liquid | ||||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||||
| 製品使用情報 |
| ||||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| 背景 | Phospholipase A2 crotoxin basic subunit CBc is a ~15 kDa protein. Heterodimer CA-CB: Crotoxin is a potent presynaptic neurotoxin that possesses phospholipase A2 (PLA2) activity and exerts a lethal action by blocking neuromuscular transmission. It consists of a non-covalent association of a basic and weakly toxic PLA2 subunit (CBa2, CBb, CBc, or CBd), with a small acidic, non-enzymatic and non-toxic subunit (CA1, CA2, CA3 or CA4). The complex acts by binding to a specific 48-kDa protein (R48) receptor located on presynaptic membranes, forming a transient ternary complex CA-CB-R48, followed by dissociation of the CA-CB complex and release of the CA subunit. At equilibrium, only the CB subunits remain associated with the specific crotoxin receptor. In addition to neurotoxicity, crotoxin has been found to exert myotoxicity, nephrotoxicity, and cardiovascular toxicity. 1. Sampaio, SC. et al. (2010) Toxicon : official journal of the International Society on Toxinology 55, 1045-60. PMID: 20109480 | ||||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-South American/Mojave rattlesnake crotoxin Antibody (Al0G)
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
