

| カタログ番号 | HT414014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-SPRY2 Polyclonal Antibody (HT414014) is a rabbit polyclonal antibody detecting SPRY2 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, Chicken, and Macaca fascicularis.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SPRY2 (Ser116-Thr305). | ||||||||
| ターゲット | Spry-2, SPRY2, Protein sprouty homolog 2 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O43597 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Protein sprouty homolog 2 (SPRY2) is a ~34 kDa protein. Antagonist of fibroblast growth factor (FGF) pathways via inhibition of FGF-mediated phosphorylation of ERK1/2. Thereby acts as an antagonist of FGF-induced retinal lens fiber differentiation, may inhibit limb bud outgrowth and may negatively modulate respiratory organogenesis. Inhibits TGFB-induced epithelial-to-mesenchymal transition in retinal lens epithelial cells. Inhibits CBL/C-CBL-mediated EGFR ubiquitination. 1. Chandramouli, S. et al. (2008) The Journal of biological chemistry 283, 1679-1691. PMID: 17974561 | ||||||||
| 注意事項 | For research use only. |
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