

| Número de catálogo | HW748014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-SREBF1/SREBP1 Polyclonal Antibody (HW748014) is a rabbit polyclonal antibody detecting SREBF1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human SREBF1/SREBP1 (Glu30-Leu490). | ||||||||
| Objetivo | Sterol regulatory element-binding protein 1, SREBF1, BHLHD1, Transcription factor SREBF1, Sterol regulatory element-binding transcription factor 1, Class D basic helix-loop-helix protein 1, bHLHd1, SREBP-1, SREBP1 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P36956 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Sterol regulatory element-binding protein 1 (SREBF1/SREBP1) is a ~121 kDa protein. Precursor of the transcription factor form (Processed sterol regulatory element-binding protein 1), which is embedded in the endoplasmic reticulum membrane. Low sterol concentrations promote processing of this form, releasing the transcription factor form that translocates into the nucleus and activates transcription of genes involved in cholesterol biosynthesis and lipid homeostasis. 1. Xu, D. et al. (2020) Nature 580, 530-535. PMID: 32322062 | ||||||||
| Nota | For research use only. |
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