

| Каталожный номер | HF541014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-STAM2 Polyclonal Antibody (HF541014) is a rabbit polyclonal antibody detecting STAM2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human STAM2 (Met1-Leu377). | ||||||||
| Цель | STAM2, Signal transducing adapter molecule 2, Hrs-binding protein, STAM-2, HBP | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | O75886 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Signal transducing adapter molecule 2 (STAM2) is a ~58 kDa protein. Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as a sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. | ||||||||
| Примечание | For research use only. |

Lane 1: Hela cell lysate
Lane 2: HepG2 cell lysate
Lane 3: PC-3 cell lysate
Lane 4: 293T cell lysate
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