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Anti-STAMBP Polyclonal Antibody (HF596014)

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Aperçu
Numéro de catalogueHF596014
Description
Anti-STAMBP Polyclonal Antibody (HF596014) is a rabbit polyclonal antibody detecting STAMBP in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human STAMBP (Lys126-Ser368).
Cible Endosome-associated ubiquitin isopeptidase, STAM-binding protein, AMSH, Associated molecule with the SH3 domain of STAM, STAMBP
Purification Purified by antigen affinity column.
Numéro d'accès O95630
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

STAM-binding protein (STAMBP) is a ~48 kDa protein. Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains. Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes.

1. McCullough, J. et al. (2004) The Journal of cell biology 166, 487-92. PMID: 15314065
2. McDonell, LM. et al. (2013) Nature genetics 45, 556-62. PMID: 23542699
3. Guo, Y. et al. (2021) The Journal of biological chemistry 297, 101107. PMID: 34425109
4. Tanaka, N. et al. (1999) The Journal of biological chemistry 274, 19129-35. PMID: 10383417
5. Itoh, F. et al. (2001) The EMBO journal 20, 4132-42. PMID: 11483516
6. Ma, YM. et al. (2007) The Journal of biological chemistry 282, 9805-9812. PMID: 17261583
Note For research use only.
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Reférences
Fiche technique
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-STAMBP Polyclonal Antibody

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