

| Número de catálogo | JN877014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Streptococcus pneumoniae Pneumolysin/ply Polyclonal Antibody (JN877014) is a rabbit polyclonal antibody detecting Pneumolysin in ELISA, IHC, WB.
Highlights
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| Reactividad de especies | Streptococcus pneumoniae | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Streptococcus pneumoniae Pneumolysin/ply (Met1-Asp471). | ||||||||
| Objetivo | Pneumolysin, PLY, Thiol-activated cytolysin, ply, spr1739 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q7ZAK5 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Pneumolysin (ply) is a ~52 kDa protein. A cholesterol-dependent toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol is required for binding to host membranes, membrane insertion and pore formation; cholesterol binding is mediated by a Thr-Leu pair in the C-terminus. Can be reversibly inactivated by oxidation. | ||||||||
| Nota | For research use only. |
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