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| カタログ番号 | VK099014 | ||||
|---|---|---|---|---|---|
| 説明 |
Anti-SV40 VP1 Polyclonal Antibody (VK099014) is a rabbit polyclonal antibody detecting Major structural protein VP1 in ELISA, IHC, WB. Suitable for Simian virus 40.
Highlights
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| 種反応性 | Simian virus 40 (SV40) | ||||
| アプリケーション | ELISA, IHC, WB | ||||
| 宿主種 | Rabbit | ||||
| クローン性 | Polyclonal | ||||
| アイソタイプ | IgG | ||||
| 免疫原 | E. coli - derived recombinant SV40 VP1 (Pro21-Gln362). | ||||
| ターゲット | Major capsid protein VP1, Major structural protein VP1 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Purified by antigen affinity column. | ||||
| アクセッション番号 | P03087 | ||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Major capsid protein VP1 is a ~39 kDa protein. Forms an icosahedral capsid with a T=7 symmetry and a 40 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with VP2 or VP3 proteins. Binds to N-glycolylneuraminic analog of the ganglioside GM1 on the cell surface to provide virion attachment to target cell. Once attached, the virion is internalized by caveolin-mediated endocytosis and traffics to the endoplasmic reticulum. Inside the endoplasmic reticulum, the protein folding machinery isomerizes VP1 interpentamer disulfide bonds, thereby triggering initial uncoating. 1. Neu, U. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 5219-24. PMID: 18353982 2. Schelhaas, M. et al. (2007) Cell 131, 516-29. PMID: 17981119 | ||||
| 注意事項 | For research use only |
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