

| Каталожный номер | VK099014 | ||||
|---|---|---|---|---|---|
| Описание |
Anti-SV40 VP1 Polyclonal Antibody (VK099014) is a rabbit polyclonal antibody detecting Major structural protein VP1 in ELISA, IHC, WB. Suitable for Simian virus 40.
Highlights
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| Реактивность видов | Simian virus 40 (SV40) | ||||
| Применения | ELISA, IHC, WB | ||||
| Хозяинский вид | Rabbit | ||||
| Клоональность | Polyclonal | ||||
| Изотип | IgG | ||||
| Иммуноген | E. coli - derived recombinant SV40 VP1 (Pro21-Gln362). | ||||
| Цель | Major capsid protein VP1, Major structural protein VP1 | ||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||
| Чистота | >95% as determined by SDS-PAGE. | ||||
| Очистка | Purified by antigen affinity column. | ||||
| Номер доступа | P03087 | ||||
| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Фон | Major capsid protein VP1 is a ~39 kDa protein. Forms an icosahedral capsid with a T=7 symmetry and a 40 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with VP2 or VP3 proteins. Binds to N-glycolylneuraminic analog of the ganglioside GM1 on the cell surface to provide virion attachment to target cell. Once attached, the virion is internalized by caveolin-mediated endocytosis and traffics to the endoplasmic reticulum. Inside the endoplasmic reticulum, the protein folding machinery isomerizes VP1 interpentamer disulfide bonds, thereby triggering initial uncoating. 1. Neu, U. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 5219-24. PMID: 18353982 2. Schelhaas, M. et al. (2007) Cell 131, 516-29. PMID: 17981119 | ||||
| Примечание | For research use only |
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