

| Numéro de catalogue | VK099044 | ||||
|---|---|---|---|---|---|
| Description |
Anti-SV40 VP2 Polyclonal Antibody (VK099044) is a rabbit polyclonal antibody detecting Minor structural protein VP2 in ELISA, IHC, WB. Suitable for Simian virus 40.
Highlights
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| Reactivité des espèces | Simian virus 40 (SV40) | ||||
| Applications | ELISA, IHC, WB | ||||
| Espèce hôte | Rabbit | ||||
| Clonalité | Polyclonal | ||||
| Isotype | IgG | ||||
| Immunogène | E. coli - derived recombinant SV40 VP2 (Met1-Arg289). | ||||
| Cible | Minor capsid protein VP2, Minor structural protein VP2 | ||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Purified by antigen affinity column. | ||||
| Numéro d'accès | P03093 | ||||
| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Contexte | Minor capsid protein VP2 is a ~38 kDa protein. Structural protein that resides within the core of the capsid surrounded by 72 VP1 pentamers. Following virus endocytosis and trafficking to the endoplasmic reticulum, VP2 and VP3 form oligomers and integrate into the endoplasmic reticulum membrane. Heterooligomer VP2-VP3 may create a viroporin for transporting the viral genome across the endoplasmic reticulum membrane to the cytoplasm. Nuclear entry of the viral DNA involves the selective exposure and importin recognition of VP2 or VP3 nuclear localization signal (shared C-terminus). Plays a role in virion assembly within the nucleus in particular through a DNA-binding domain located in the C-terminal region. | ||||
| Note | For research use only |
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