Anti-SYK Polyclonal Antibody (HW747014)

Name: Anti-SYK Polyclonal Antibody
Brand: abinScience
SKU: HW747014
Price: 168 USD
Availability: InStock

Даташит Поделиться продуктом Копировать информацию

Цена(USD): --

Спецификация:

50ug
100ug

Количество:

Свяжитесь с нами

Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HW747014

Описание

Anti-SYK Polyclonal Antibody (HW747014) is a rabbit polyclonal antibody detecting SYK in ELISA, IHC, WB. Suitable for Human, Mouse, Pig, Rat, and Chicken.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant human SYK (Asp374-Asn635).

Цель

Tyrosine-protein kinase SYK, EC:2.7.10.2, Spleen tyrosine kinase, p72-Syk, SYK

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

P43405, P48025, Q00655, Q64725, F1N9Y5

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Tyrosine-protein kinase SYK is a ~72 kDa protein. Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the receptor can also be indirect and mediated by adapter proteins containing ITAM or partial hemITAM domains. The phosphorylation of the ITAM domains is generally mediated by SRC subfamily kinases upon engagement of the receptor.

1. Urzainqui, A. et al. (2002) Immunity 17, 401-12. PMID: 12387735

2. Wang, L. et al. (2021) Nature genetics 53, 500-510. PMID: 33782605

3. Chiu, CW. et al. (2002) The EMBO journal 21, 6461-72. PMID: 12456653

4. Shim, EK. et al. (2004) FEBS letters 575, 35-40. PMID: 15388330

5. M Gagné, L. et al. (2021) The Journal of biological chemistry 297, 101291. PMID: 34634301

6. Law, CL. et al. (1996) Molecular and cellular biology 16, 1305-15. PMID: 8657103

7. Ratthé, C. et al. (2004) Journal of leukocyte biology 76, 162-8. PMID: 15123770

Примечание

For research use only

Изображения

Ссылки

Даташит

Anti-SYK Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-SYK Polyclonal Antibody (HW747014)

Обзор

Изображения

Ссылки

Даташит

SDS