Anti-Human TACR2 Polyclonal Antibody (HB728014)

Name: Anti-Human TACR2 Polyclonal Antibody
Brand: abinScience
SKU: HB728014
Price: 96 USD
Availability: InStock

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Especificación:

20ug
50ug
100ug

Número:

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SDS

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Número de catálogo

HB728014

Descripción

Anti-Human TACR2 Polyclonal Antibody (HB728014) is a rabbit polyclonal antibody detecting TACR2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human TACR2 (Asn311-Ser366).

Objetivo

NK-2 receptor, NKNAR, Neurokinin A receptor, SKR, Tachykinin receptor 2, TACR2, TAC2R, Substance-K receptor, NK2R, NK-2R

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Purified by antigen affinity column.

Número de acceso

P21452

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Substance-K receptor (TACR2) is a ~44 kDa protein. This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). Is also able to bind and respond to tachynins substance P and neurokinin B/neuromedin-K. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P. Substance K binding to its receptor triggers G protein-coupled receptor signaling via activation of G(q) and phosphatidylinositol hydrolysis by phospholipase C. Substance K binding also triggers signaling via activation of adenylate cyclase activity which results in increased intracellular levels of cyclic AMP (cAMP).

1. Cyr, C. et al. (1991) Annals of the New York Academy of Sciences 632, 426-7. PMID: 1659297

2. Kris, RM. et al. (1991) Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2, 15-22. PMID: 1848773

3. Edgerton, MD. et al. (1994) FEBS letters 354, 195-9. PMID: 7957923

4. Sun, W. et al. (2022) Cell discovery 8, 72. PMID: 35882833

Nota

For research use only.

Imágenes

Western blot

Western blot analysis was performed using anti-TACR2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse heart lysate
Lane 2: Mouse lung lysate
Lane 3: Mouse brain lysate
Lane 4: Rat heart lysate
Lane 5: Rat brain lysate
Western blot

Western blot analysis was performed using anti-TACR2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse stomach lysate

Referencias

Datasheet

Anti-Human TACR2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-Human TACR2 Polyclonal Antibody (HB728014)

Vista general

Imágenes

Referencias

Datasheet

SDS