Anti-Human TACR2 Polyclonal Antibody (HB728014)

Name: Anti-Human TACR2 Polyclonal Antibody
Brand: abinScience
SKU: HB728014
Price: 96 USD
Availability: InStock

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SDS

Обзор

Каталожный номер

HB728014

Описание

Anti-Human TACR2 Polyclonal Antibody (HB728014) is a rabbit polyclonal antibody detecting TACR2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human TACR2 (Asn311-Ser366).

Цель

NK-2 receptor, NKNAR, Neurokinin A receptor, SKR, Tachykinin receptor 2, TACR2, TAC2R, Substance-K receptor, NK2R, NK-2R

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Purified by antigen affinity column.

Номер доступа

P21452

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Substance-K receptor (TACR2) is a ~44 kDa protein. This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). Is also able to bind and respond to tachynins substance P and neurokinin B/neuromedin-K. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P. Substance K binding to its receptor triggers G protein-coupled receptor signaling via activation of G(q) and phosphatidylinositol hydrolysis by phospholipase C. Substance K binding also triggers signaling via activation of adenylate cyclase activity which results in increased intracellular levels of cyclic AMP (cAMP).

1. Cyr, C. et al. (1991) Annals of the New York Academy of Sciences 632, 426-7. PMID: 1659297

2. Kris, RM. et al. (1991) Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2, 15-22. PMID: 1848773

3. Edgerton, MD. et al. (1994) FEBS letters 354, 195-9. PMID: 7957923

4. Sun, W. et al. (2022) Cell discovery 8, 72. PMID: 35882833

Примечание

For research use only.

Изображения

Western blot

Western blot analysis was performed using anti-TACR2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse heart lysate
Lane 2: Mouse lung lysate
Lane 3: Mouse brain lysate
Lane 4: Rat heart lysate
Lane 5: Rat brain lysate
Western blot

Western blot analysis was performed using anti-TACR2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse stomach lysate

Ссылки

Даташит

Anti-Human TACR2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-Human TACR2 Polyclonal Antibody (HB728014)

Обзор

Изображения

Ссылки

Даташит

SDS