

| カタログ番号 | HS849014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-TAF12 Polyclonal Antibody (HS849014) is a rabbit polyclonal antibody detecting TAF12 in ELISA, IHC, WB. Suitable for Human, Mouse, and Bovine.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human TAF12 (Met1-Lys161). | ||||||||
| ターゲット | TAF2J, Transcription initiation factor TFIID subunit 12, TAFII20, TAFII20/TAFII15, TAF15, TAF12, TAFII-20/TAFII-15, Transcription initiation factor TFIID 20/15 kDa subunits | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q16514 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Transcription initiation factor TFIID subunit 12 (TAF12) is a ~17 kDa protein. The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the TATA-binding protein-free TAF complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. 1. Chen, X. et al. (2021) Science (New York, N.Y.) 372. PMID: 33795473 2. Brand, M. et al. (1999) The Journal of biological chemistry 274, 18285-9. PMID: 10373431 3. Mengus, G. et al. (1995) The EMBO journal 14, 1520-31. PMID: 7729427 4. Hoffmann, A. et al. (1996) Nature 380, 356-9. PMID: 8598932 5. Hoffmann, A. et al. (1996) The Journal of biological chemistry 271, 18194-202. PMID: 8663456 6. Ogryzko, VV. et al. (1998) Cell 94, 35-44. PMID: 9674425 7. Vassilev, A. et al. (1998) Molecular cell 2, 869-75. PMID: 9885574 | ||||||||
| 注意事項 | For research use only. |
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