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| カタログ番号 | HY086034 | ||||||
|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Tau (phosphe T217) Polyclonal Antibody (HY086034) is a rabbit polyclonal antibody detecting tau in WB, ELISA. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||
| アプリケーション | WB, ELISA | ||||||
| 宿主種 | Rabbit | ||||||
| クローン性 | Polyclonal | ||||||
| アイソタイプ | IgG | ||||||
| ターゲット | MAPT, MAPTL, MTBT1, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, Paired helical filament-tau, TAU | ||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||
| 純度 | >90% as determined by SDS-PAGE. | ||||||
| 精製 | Purified by antigen affinity column. | ||||||
| アクセッション番号 | P10636 | ||||||
| 形態 | Liquid | ||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||
| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| 別名 | Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT | ||||||
| 背景 | Microtubule-associated protein tau is a ~78 kDa protein. Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. 1. Yoshida, H. et al. (2012) Journal of neurochemistry 120, 165-76. PMID: 21985311 2. Sandberg, A. et al. (2020) Neurobiology of disease 146, 105079. PMID: 32961270 | ||||||
| 注意事項 | For research use only. |
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