

| カタログ番号 | HT202014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-TBX3 Polyclonal Antibody (HT202014) is a rabbit polyclonal antibody detecting TBX3 in ELISA, IHC, WB. Suitable for Mouse, Dog, Danio rerio, Chicken, and Human.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human TBX3 (Leu107-Thr220). | ||||||||
| ターゲット | TBX3, T-box transcription factor TBX3, T-box protein 3 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O15119 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | T-box transcription factor TBX3 is a ~79 kDa protein. Transcriptional repressor involved in developmental processes. Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence, or a half-site, which are present in the regulatory region of several genes. Probably plays a role in limb pattern formation. Required for mammary placode induction, and maintenance of the mammary buds during development. Involved in branching morphogenesis in both developing lungs and adult mammary glands, via negative modulation of target genes; acting redundantly with TBX2. 1. He, Ml. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 10212-7. PMID: 10468588 2. Lingbeek, ME. et al. (2002) The Journal of biological chemistry 277, 26120-7. PMID: 12000749 3. Martin, N. et al. (2012) The EMBO journal 31, 95-109. PMID: 22002537 | ||||||||
| 注意事項 | For research use only. |

Western blot analysis was performed using anti-IBX3 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse lung lysate
Lane 2: Rat lung lysate


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