

| Numéro de catalogue | HA637014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-TEC Polyclonal Antibody (HA637014) is a rabbit polyclonal antibody detecting Tyrosine-protein kinase Tec; 2.7.10.2; TEC; PSCTK4 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant human TEC (Glu182-Arg631). | ||||||||
| Cible | Tyrosine-protein kinase Tec; 2.7.10.2; TEC; PSCTK4 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P42680, P24604 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Tyrosine-protein kinase Tec is a ~73 kDa protein. Non-receptor tyrosine kinase that contributes to signaling from many receptors and participates as a signal transducer in multiple downstream pathways, including regulation of the actin cytoskeleton. Plays a redundant role to ITK in regulation of the adaptive immune response. Regulates the development, function and differentiation of conventional T-cells and nonconventional NKT-cells. Required for TCR-dependent IL2 gene induction. Phosphorylates DOK1, one CD28-specific substrate, and contributes to CD28-signaling. | ||||||||
| Note | For research use only |

Western blot analysis was performed using anti-TEC polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse spleen lysate
Lane 2: Rat spleen lysate
Lane 3: Rat liver lysate
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