

| Numéro de catalogue | HC493014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-TFDP1 Polyclonal Antibody (HC493014) is a rabbit polyclonal antibody detecting TFDP1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Bovine.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human TFDP1 (Gly6-Asp410). | ||||||||
| Cible | DRTF1-polypeptide 1, DRTF1, E2F dimerization partner 1, TFDP1, DP1, Transcription factor Dp-1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q14186 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Transcription factor Dp-1 (TFDP1) is a ~45 kDa protein. Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters. 1. Wu, CL. et al. (1995) Molecular and cellular biology 15, 2536-46. PMID: 7739537 2. Helin, K. et al. (1993) Genes & development 7, 1850-61. PMID: 8405995 3. Zaragoza, K. et al. (2010) Molecular and cellular biology 30, 2293-304. PMID: 20176812 | ||||||||
| Note | For research use only. |
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