

| Numéro de catalogue | VK727044 | ||||||||
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| Description |
Anti-TGEV RBD Polyclonal Antibody (VK727044) is a rabbit polyclonal antibody detecting TGEV RBD. Suitable for Porcine transmissible gastroenteritis coronavirus, Feline coronavirus, and Porcine respiratory coronavirus.
Highlights
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| Reactivité des espèces | Porcine transmissible gastroenteritis coronavirus (TGEV), Feline coronavirus (FCoV) | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant TGEV RBD (Pro521-Pro667). | ||||||||
| Cible | E2, Peplomer protein, S, S glycoprotein, Spike glycoprotein | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Pureté | >95% as determined by SDS-PAGE. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P07946 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | Spike glycoprotein (RBD) is a ~160 kDa protein. S1 region attaches the virion to the cell membrane by interacting with host ANPEP/aminopeptidase N, initiating the infection. Binding to the receptor probably induces conformational changes in the S glycoprotein unmasking the fusion peptide of S2 region and activating membranes fusion. S2 region belongs to the class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. | ||||||||
| Note | For research use only |



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