Anti-TGFBR3 Polyclonal Antibody (HA790014)

Name: Anti-TGFBR3 Polyclonal Antibody
Brand: abinScience
SKU: HA790014
Price: 96 USD
Availability: InStock

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Spécification :

20ug
50ug
100ug

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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HA790014

Description

Anti-TGFBR3 Polyclonal Antibody (HA790014) is a rabbit polyclonal antibody detecting Transforming growth factor beta receptor type 3; TGF-beta receptor type 3; TGFR-3; Betaglycan; Transforming growth factor beta receptor III; TGF-beta receptor type III; TGFBR3 in ELISA, IHC, WB. Suitable for Human, Pig, Rat, and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant human TGFBR3 (Ser36-Glu360).

Cible

Transforming growth factor beta receptor type 3; TGF-beta receptor type 3; TGFR-3; Betaglycan; Transforming growth factor beta receptor III; TGF-beta receptor type III; TGFBR3

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

Q03167, P35054, P26342, O88393

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Transforming growth factor beta receptor type 3 (TGFBR3) is a ~93 kDa protein. Cell surface receptor that regulates diverse cellular processes including cell proliferation, differentiation, migration, and apoptosis. Initiates BMP, inhibin, and TGF-beta signaling pathways by interacting with different ligands including TGFB1, BMP2, BMP5, BMP7 or GDF5. Alternatively, acts as a cell surface coreceptor for BMP ligands, serving to enhance ligand binding by differentially regulating BMPR1A/ALK3 and BMPR1B/ALK6 receptor trafficking. Promotes epithelial cell adhesion, focal adhesion formation and integrin signaling during epithelial cell spreading on fibronectin. By interacting with the scaffolding protein beta-arrestin2/ARRB2, regulates migration or actin cytoskeleton and promotes the activation of CDC42 as well as the inhibition of NF-kappa-B.

1. Chen, W. et al. (2003) Science (New York, N.Y.) 301, 1394-7. PMID: 12958365

2. Mythreye, K. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 8221-6. PMID: 19416857

3. Kirkbride, KC. et al. (2008) The Journal of biological chemistry 283, 7628-37. PMID: 18184661

4. Lee, NY. et al. (2009) Molecular biology of the cell 20, 4362-70. PMID: 19726563

5. Mythreye, K. et al. (2013) Oncogene 32, 1416-27. PMID: 22562249

6. You, HJ. et al. (2009) Carcinogenesis 30, 1281-7. PMID: 19325136

Note

For research use only

Images

Western blot

Western blot analysis was performed using anti-TGFBR3 polyclonal antibody at 1ug/mL on various samples.
Lane 1: NIH3T3 cell lysate
Lane 2: PC-12 cell lysate

Reférences

Fiche technique

Anti-TGFBR3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-TGFBR3 Polyclonal Antibody (HA790014)

Aperçu

Images

Reférences

Fiche technique

SDS