Anti-TGFBR3 Polyclonal Antibody (HA790014)

Name: Anti-TGFBR3 Polyclonal Antibody
Brand: abinScience
SKU: HA790014
Price: 96 USD
Availability: InStock

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Каталожный номер

HA790014

Описание

Anti-TGFBR3 Polyclonal Antibody (HA790014) is a rabbit polyclonal antibody detecting Transforming growth factor beta receptor type 3; TGF-beta receptor type 3; TGFR-3; Betaglycan; Transforming growth factor beta receptor III; TGF-beta receptor type III; TGFBR3 in ELISA, IHC, WB. Suitable for Human, Pig, Rat, and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant human TGFBR3 (Ser36-Glu360).

Цель

Transforming growth factor beta receptor type 3; TGF-beta receptor type 3; TGFR-3; Betaglycan; Transforming growth factor beta receptor III; TGF-beta receptor type III; TGFBR3

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

Q03167, P35054, P26342, O88393

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Transforming growth factor beta receptor type 3 (TGFBR3) is a ~93 kDa protein. Cell surface receptor that regulates diverse cellular processes including cell proliferation, differentiation, migration, and apoptosis. Initiates BMP, inhibin, and TGF-beta signaling pathways by interacting with different ligands including TGFB1, BMP2, BMP5, BMP7 or GDF5. Alternatively, acts as a cell surface coreceptor for BMP ligands, serving to enhance ligand binding by differentially regulating BMPR1A/ALK3 and BMPR1B/ALK6 receptor trafficking. Promotes epithelial cell adhesion, focal adhesion formation and integrin signaling during epithelial cell spreading on fibronectin. By interacting with the scaffolding protein beta-arrestin2/ARRB2, regulates migration or actin cytoskeleton and promotes the activation of CDC42 as well as the inhibition of NF-kappa-B.

1. Chen, W. et al. (2003) Science (New York, N.Y.) 301, 1394-7. PMID: 12958365

2. Mythreye, K. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 8221-6. PMID: 19416857

3. Kirkbride, KC. et al. (2008) The Journal of biological chemistry 283, 7628-37. PMID: 18184661

4. Lee, NY. et al. (2009) Molecular biology of the cell 20, 4362-70. PMID: 19726563

5. Mythreye, K. et al. (2013) Oncogene 32, 1416-27. PMID: 22562249

6. You, HJ. et al. (2009) Carcinogenesis 30, 1281-7. PMID: 19325136

Примечание

For research use only

Изображения

Western blot

Western blot analysis was performed using anti-TGFBR3 polyclonal antibody at 1ug/mL on various samples.
Lane 1: NIH3T3 cell lysate
Lane 2: PC-12 cell lysate

Ссылки

Даташит

Anti-TGFBR3 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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Anti-TGFBR3 Polyclonal Antibody (HA790014)

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