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Anti-TH Polyclonal Antibody (HY108014)

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Aperçu
Numéro de catalogueHY108014
Description
Anti-TH Polyclonal Antibody (HY108014) is a rabbit polyclonal antibody detecting TH in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human TH (Met1-Ile260).
Cible Tyrosine 3-hydroxylase, TYH, Tyrosine 3-monooxygenase, TH
Purification Purified by antigen affinity column.
Numéro d'accès P07101
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Tyrosine 3-monooxygenase (TH) is a ~58 kDa protein. Catalyzes the conversion of L-tyrosine to L-dihydroxyphenylalanine (L-Dopa), the rate-limiting step in the biosynthesis of catecholamines, dopamine, noradrenaline, and adrenaline. Uses tetrahydrobiopterin and molecular oxygen to convert tyrosine to L-Dopa (PubMed:15287903, PubMed:1680128, PubMed:17391063, PubMed:24753243, PubMed:34922205, PubMed:8528210, Ref.18). In addition to tyrosine, is able to catalyze the hydroxylation of phenylalanine and tryptophan with lower specificity. Positively regulates the regression of retinal hyaloid vessels during postnatal development.

1. Sura, GR. et al. (2004) Journal of neurochemistry 90, 970-8. PMID: 15287903
2. Le Bourdellès, B. et al. (1991) The Journal of biological chemistry 266, 17124-30. PMID: 1680128
3. Roma, J. et al. (2007) Biological chemistry 388, 419-26. PMID: 17391063
4. Fossbakk, A. et al. (2014) Human mutation 35, 880-90. PMID: 24753243
5. Inukai, S. et al. (2022) Biochemical and biophysical research communications 589, 209-214. PMID: 34922205
6. Knappskog, PM. et al. (1995) Human molecular genetics 4, 1209-12. PMID: 8528210
Note For research use only.
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Fiche technique
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-TH Polyclonal Antibody

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