

| Numéro de catalogue | HW432014 | ||||||||
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| Description |
Anti-THOP1 Polyclonal Antibody (HW432014) is a rabbit polyclonal antibody detecting THOP1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pig.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human THOP1 (Asn451-Thr597). | ||||||||
| Cible | Thimet oligopeptidase, THOP1, MP78, Endopeptidase 24.15 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P52888 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Thimet oligopeptidase (THOP1) is a ~78 kDa protein. Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the amyloid-beta precursor protein and generate amyloidogenic fragments. Also acts as a regulator of cannabinoid signaling pathway by mediating degradation of hemopressin, an antagonist peptide of the cannabinoid receptor CNR1. 1. Lim, EJ. et al. (2007) The Journal of biological chemistry 282, 9722-9732. PMID: 17251185 2. Thompson, A. et al. (1995) Biochemical and biophysical research communications 213, 66-73. PMID: 7639763 | ||||||||
| Note | For research use only. |
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