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| カタログ番号 | HW432014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-THOP1 Polyclonal Antibody (HW432014) is a rabbit polyclonal antibody detecting THOP1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pig.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human THOP1 (Asn451-Thr597). | ||||||||
| ターゲット | Thimet oligopeptidase, THOP1, MP78, Endopeptidase 24.15 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P52888 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Thimet oligopeptidase (THOP1) is a ~78 kDa protein. Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the amyloid-beta precursor protein and generate amyloidogenic fragments. Also acts as a regulator of cannabinoid signaling pathway by mediating degradation of hemopressin, an antagonist peptide of the cannabinoid receptor CNR1. 1. Lim, EJ. et al. (2007) The Journal of biological chemistry 282, 9722-9732. PMID: 17251185 2. Thompson, A. et al. (1995) Biochemical and biophysical research communications 213, 66-73. PMID: 7639763 | ||||||||
| 注意事項 | For research use only. |
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