

| Número de catálogo | HC876014 | ||||||||
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| Descripción |
Anti-TIMM23 Polyclonal Antibody (HC876014) is a rabbit polyclonal antibody detecting TIMM23 in ELISA, IHC, WB. Suitable for Human, Rat, and Mouse.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant TIMM23 (Glu2-Arg72). | ||||||||
| Objetivo | Mitochondrial import inner membrane translocase subunit Tim23, TIM23, TIMM23 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | O14925, O35093, Q9WTQ8, Q5SRD1 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Mitochondrial import inner membrane translocase subunit Tim23 is a ~21 kDa protein. Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has a role in the activation of stress-induced mitophagy by protecting PINK1 from OMA1-mediated degradation and facilitating its accumulation at the outer mitochondrial membrane in response to depolarization. 1. Bauer, MF. et al. (1999) Journal of molecular biology 289, 69-82. PMID: 10339406 2. Akabane, S. et al. (2023) Cell reports 42, 112454. PMID: 37160114 | ||||||||
| Nota | For research use only |
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