Anti-TK1 Polyclonal Antibody (HY157014)

Name: Anti-TK1 Polyclonal Antibody
Brand: abinScience
SKU: HY157014
Price: 96 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HY157014

Description

Anti-TK1 Polyclonal Antibody (HY157014) is a rabbit polyclonal antibody detecting TK1 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, Cricetulus griseus, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human TK1 (Met1-Asn234).

Cible

Thymidine kinase, cytosolic, TK1

Purification

Purified by antigen affinity column.

Numéro d'accès

P04183

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Thymidine kinase, cytosolic (TK1) is a ~25 kDa protein. Cell-cycle-regulated enzyme of importance in nucleotide metabolism. Catalyzes the first enzymatic step in the salvage pathway converting thymidine into thymidine monophosphate. Transcriptional regulation limits expression to the S phase of the cell cycle and transient expression coincides with the oscillation in the intracellular dTTP concentration (Probable). Also important for the activation of anticancer and antiviral nucleoside analog prodrugs such as 1-b-d-arabinofuranosylcytosine (AraC) and 3c-azido-3c-deoxythymidine (AZT).

1. Chang, ZF. et al. (1998) The Journal of biological chemistry 273, 12095-100. PMID: 9575153

2. Skovgaard, T. et al. (2012) The FEBS journal 279, 1777-87. PMID: 22385435

Note

For research use only.

Images

Reférences

Fiche technique

Anti-TK1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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