Anti-Tocilizumab Polyclonal Antibody (AY583024)

Name: Anti-Tocilizumab Polyclonal Antibody
Brand: abinScience
SKU: AY583024
Price: 168 USD
Availability: InStock

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50ug
100ug
1mg

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Aperçu
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SDS

Aperçu

Numéro de catalogue

AY583024

Description

Anti-Tocilizumab Polyclonal Antibody (AY583024) is a rabbit polyclonal antibody detecting Tocilizumab in ELISA.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.

Reactivité des espèces

General

Applications

ELISA

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

Tocilizumab

Cible

Rabbit polyclonal to Actemra.

Spécificité

The product is specific for Tocilizumab. This antibody serves as an excellent positive control for Tocilizumab immunogenicity (ADA) assays.

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>90% as determined by SDS-PAGE.

Purification

Purified by antigen affinity column.

Numéro d'accès

CAS: 375823-41-9

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Tocilizumab (Actemra) is a humanized monoclonal antibody that is developed by Hoffmann–La Roche and Chugai for the treatment of patients with rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a severe form of arthritis in children. Tocilizumab binds to the interleukin-6 receptor (IL-6R) and blocks its interaction with interleukin 6 (IL-6), hindering IL-6 from exerting its pro-inflammatory effects.
• Evaluation of a biosensor immunoassay for simultaneous characterization of isotype and binding region of human anti-tocilizumab antibodies with control by surrogate standards., PMID:19379704

Note

For research use only.

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