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Anti-Toxoplasma gondii SAG1/Major surface antigen p30 Recombinant Antibody (SAA2154) (JN902013)

Anti-Toxoplasma gondii SAG1/Major surface antigen p30 Recombinant Antibody (SAA2154)
Anti-Toxoplasma gondii SAG1/Major surface antigen p30 Recombinant Antibody (SAA2154)
Anti-Toxoplasma gondii SAG1/Major surface antigen p30 Recombinant Antibody (SAA2154)
Anti-Toxoplasma gondii SAG1/Major surface antigen p30 Recombinant Antibody (SAA2154)
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Aperçu
Numéro de catalogueJN902013
Reactivité des espècesToxoplasma gondii
ApplicationsELISA, WB
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG1
ID de cloneSAA2154
Cible Major surface antigen p30
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P13664
RRID Anti-Toxoplasma gondii SAG1/Major surface antigen p30 Antibody (SAA2154) (abinScience Cat# JN902013, RRID:AB_3729523)
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:2000-1:20000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

Major surface antigen p30 (SAG1) is a ~34 kDa protein. Mediates binding to host cells and is especially important for parasite attachment and fitness in IFN-gamma/IFNG-stimulated host cells. May regulate binding between human S100A6 and vimentin (VIM) for cytoskeleton organization during the early stages of invasion into host cells. Promotes TNF secretion in host cells probably by enhancing binding between human VIM and PRKCQ and activating NF-kappa-B pathway. Promotes viability of host cells to satisfy the survival needs of parasites through the interaction with human RACK1.

1. Robinson, SA. et al. (2004) Parasitology 128, 391-6. PMID: 15151144
2. Cohen, O. et al. (2025) Infection and immunity 93, e0001025. PMID: 40607979
3. Zhou, LJ. et al. (2021) iScience 24, 103514. PMID: 34950858
4. Wang, D. et al. (2024) Acta tropica 251, 107112. PMID: 38157925
Note For research use only.
Images
  • Anti-Toxoplasma gondii SAG1/Major surface antigen p30 Recombinant Antibody (SAA2154)

    SDS-PAGE

    SDS-PAGE for Anti-Toxoplasma gondii SAG1/Major surface antigen p30 Recombinant Antibody (SAA2154)

  • Anti-Toxoplasma gondii SAG1/Major surface antigen p30 Recombinant Antibody (SAA2154)

    Western blot

    Western blot analysis was performed using anti-/ monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant Toxoplasma gondii SAG1/Major surface antigen p30(Catalog No: JN902012)
    Lane 2: negative control
    Lane 3: negative control

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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