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| カタログ番号 | HV557014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-TP63 Polyclonal Antibody (HV557014) is a rabbit polyclonal antibody detecting TP63 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human TP63 (Ser41-Cys339). | ||||||||
| ターゲット | Keratinocyte transcription factor KET, P63, KET, Tumor protein p73-like, p63, P73L, CUSP, P73H, p40, Tumor protein 63, TP73L, Transformation-related protein 63, TP63, Chronic ulcerative stomatitis protein, p73L, p51 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9H3D4 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Tumor protein 63 (TP63/p40) is a ~76 kDa protein. Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-TP63 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Rat heart lysate
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