Anti-TPMT Polyclonal Antibody (HW491014)

Name: Anti-TPMT Polyclonal Antibody
Brand: abinScience
SKU: HW491014
Price: 168 USD
Availability: InStock

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SDS

Обзор

Каталожный номер

HW491014

Описание

Anti-TPMT Polyclonal Antibody (HW491014) is a rabbit polyclonal antibody detecting TPMT in ELISA, IHC, WB. Suitable for Human, Pan troglodytes, and Pongo pygmaeus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human TPMT (Leu26-His227).

Цель

Thiopurine methyltransferase, Thiopurine S-methyltransferase, TPMT

Очистка

Purified by antigen affinity column.

Номер доступа

P51580

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Thiopurine S-methyltransferase (TPMT) is a ~28 kDa protein. Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine (also called mercaptopurine, 6-MP or its brand name Purinethol) and 6-thioguanine (also called tioguanine or 6-TG) using S-adenosyl-L-methionine as the methyl donor. TPMT activity modulates the cytotoxic effects of thiopurine prodrugs. A natural substrate for this enzyme has yet to be identified.

1. Peng, Y. et al. (2008) Biochemistry 47, 6216-25. PMID: 18484748

2. Weinshilboum, RM. et al. (1978) Clinica chimica acta; international journal of clinical chemistry 85, 323-33. PMID: 657528

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-TPMT Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа