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| カタログ番号 | JN038014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Treponema pallidum TPP47 Polyclonal Antibody (JN038014) is a rabbit polyclonal antibody detecting Treponema Pallidum (TP in ELISA, IHC, WB.
Highlights
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| 種反応性 | Treponema pallidum | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Treponema pallidum TPP47 (Cys20-Gln434). | ||||||||
| ターゲット | Putative DD-carboxypeptidase TP_0574, 3.4.-.-, 47 kDa lipoprotein, Tp47, Tpp47, 47 kDa membrane antigen, 47-kilodalton major integral membrane immunogen, TP_0574, Treponema Pallidum (TP, Syphilis) | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P29723 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Putative DD-carboxypeptidase TP_0574 (TPP47) is a ~47 kDa protein. A possible D,D-carboxypeptidase, that releases amino acids sequentially from a proteins C-terminus. Has zinc-dependent carboxypeptidase activity on synthetic depsipeptide substrates. May serve to decrease cross-linking of peptidoglycan, promoting the highly sinusous motility of this spirochaete (Probable). Overexpression of the whole protein in E.coli leads to aberrant cell morphology and extrusion of the cytoplasm, while overexpression of a construct with the first 62 resides of the protein fused to PhoA does have this effect, suggesting the whole protein, not the lipoprotein moiety, is toxic. Binds penicillin. 1. Deka, RK. et al. (2002) The Journal of biological chemistry 277, 41857-64. PMID: 12196546 2. Weigel, LM. et al. (1994) Proceedings of the National Academy of Sciences of the United States of America 91, 11611-5. PMID: 7972112 3. Radolf, JD. et al. (1989) Infection and immunity 57, 1248-54. PMID: 2647634 | ||||||||
| 注意事項 | For research use only. |
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