

| Каталожный номер | JN038014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Treponema pallidum TPP47 Polyclonal Antibody (JN038014) is a rabbit polyclonal antibody detecting Treponema Pallidum (TP in ELISA, IHC, WB.
Highlights
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| Реактивность видов | Treponema pallidum | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Treponema pallidum TPP47 (Cys20-Gln434). | ||||||||
| Цель | Putative DD-carboxypeptidase TP_0574, 3.4.-.-, 47 kDa lipoprotein, Tp47, Tpp47, 47 kDa membrane antigen, 47-kilodalton major integral membrane immunogen, TP_0574, Treponema Pallidum (TP, Syphilis) | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P29723 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Putative DD-carboxypeptidase TP_0574 (TPP47) is a ~47 kDa protein. A possible D,D-carboxypeptidase, that releases amino acids sequentially from a proteins C-terminus. Has zinc-dependent carboxypeptidase activity on synthetic depsipeptide substrates. May serve to decrease cross-linking of peptidoglycan, promoting the highly sinusous motility of this spirochaete (Probable). Overexpression of the whole protein in E.coli leads to aberrant cell morphology and extrusion of the cytoplasm, while overexpression of a construct with the first 62 resides of the protein fused to PhoA does have this effect, suggesting the whole protein, not the lipoprotein moiety, is toxic. Binds penicillin. 1. Deka, RK. et al. (2002) The Journal of biological chemistry 277, 41857-64. PMID: 12196546 2. Weigel, LM. et al. (1994) Proceedings of the National Academy of Sciences of the United States of America 91, 11611-5. PMID: 7972112 3. Radolf, JD. et al. (1989) Infection and immunity 57, 1248-54. PMID: 2647634 | ||||||||
| Примечание | For research use only. |
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