

| Número de catálogo | HB439014 | ||||||||
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| Descripción |
Anti-TRIP4 Polyclonal Antibody (HB439014) is a rabbit polyclonal antibody detecting Activating signal cointegrator 1; ASC-1; Thyroid receptor-interacting protein 4; TR-interacting protein 4; TRIP-4; TRIP4; RQT4 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant human TRIP4 (Asp424-Val581). | ||||||||
| Objetivo | Activating signal cointegrator 1; ASC-1; Thyroid receptor-interacting protein 4; TR-interacting protein 4; TRIP-4; TRIP4; RQT4 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q15650, Q9QXN3 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Activating signal cointegrator 1 (TRIP4) is a ~66 kDa protein. Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation. Also involved in androgen receptor transactivation. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. 1. Kim, HJ. et al. (1999) Molecular and cellular biology 19, 6323-32. PMID: 10454579 2. Yoo, HM. et al. (2014) Molecular cell 56, 261-274. PMID: 25219498 3. Jung, DJ. et al. (2002) Molecular and cellular biology 22, 5203-11. PMID: 12077347 4. Knierim, E. et al. (2016) American journal of human genetics 98, 473-489. PMID: 26924529 5. Hashimoto, S. et al. (2020) Scientific reports 10, 3422. PMID: 32099016 | ||||||||
| Nota | For research use only |
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