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Anti-TRIP4 Polyclonal Antibody (HB439014)

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概要
カタログ番号HB439014
説明
Anti-TRIP4 Polyclonal Antibody (HB439014) is a rabbit polyclonal antibody detecting Activating signal cointegrator 1; ASC-1; Thyroid receptor-interacting protein 4; TR-interacting protein 4; TRIP-4; TRIP4; RQT4 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
種反応性Human, Mouse
アプリケーションELISA, IHC, WB
宿主種Rabbit
クローン性Polyclonal
アイソタイプIgG
免疫原 E. coli - derived recombinant human TRIP4 (Asp424-Val581).
ターゲット Activating signal cointegrator 1; ASC-1; Thyroid receptor-interacting protein 4; TR-interacting protein 4; TRIP-4; TRIP4; RQT4
エンドトキシンレベル Please contact with the lab for this information.
精製 Purified by antigen affinity column.
アクセッション番号 Q15650, Q9QXN3
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報
アプリケーション 希釈
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Activating signal cointegrator 1 (TRIP4) is a ~66 kDa protein. Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation. Also involved in androgen receptor transactivation. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1.

1. Kim, HJ. et al. (1999) Molecular and cellular biology 19, 6323-32. PMID: 10454579
2. Yoo, HM. et al. (2014) Molecular cell 56, 261-274. PMID: 25219498
3. Jung, DJ. et al. (2002) Molecular and cellular biology 22, 5203-11. PMID: 12077347
4. Knierim, E. et al. (2016) American journal of human genetics 98, 473-489. PMID: 26924529
5. Hashimoto, S. et al. (2020) Scientific reports 10, 3422. PMID: 32099016
注意事項 For research use only
イメージ
参考文献
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