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| カタログ番号 | HV333014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-TRPC6 Polyclonal Antibody (HV333014) is a rabbit polyclonal antibody detecting TRPC6 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human TRPC6 (Met1-Leu192). | ||||||||
| ターゲット | TrpC6, TRP-6, Short transient receptor potential channel 6, Transient receptor protein 6, TRP6, TRPC6 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9Y210 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Short transient receptor potential channel 6 (TRPC6) is a ~106 kDa protein. Forms a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Does not seem to be activated by intracellular calcium store depletion. 1. Heeringa, SF. et al. (2009) PloS one 4, e7771. PMID: 19936226 2. Hofstra, JM. et al. (2013) Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 28, 1830-8. PMID: 23291369 3. Riehle, M. et al. (2016) Journal of the American Society of Nephrology : JASN 27, 2771-83. PMID: 26892346 4. Hofmann, T. et al. (1999) Nature 397, 259-63. PMID: 9930701 | ||||||||
| 注意事項 | For research use only. |
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